The 12 best luxury hotels in Panama
A Jesuit monastery in the old town, a treehouse above the Caribbean mangroves or a resort inside a volcanic crater: among the luxury hotels in Panama, our travel advisors find the right one for your trip with you and advise you personally. You receive exclusive suitespot benefits at every one of our hotels, at the regular hotel rate.
Luxury hotels in Panama by destination
Where would you like to go? For Panama City we have our own guide with our recommendations for each neighborhood, prices and your benefits.
The most popular luxury hotels in Panama
Your selection in Panama starts with these hotels: from the restored colonial buildings of Casco Viejo to the island resort in the Caribbean. Your benefits are included with every booking through suitespot.
Unlock exclusive benefits as a premium member
Unlock exclusive benefits as a premium member
Unlock exclusive benefits as a premium member
Unlock exclusive benefits as a premium member
Unlock exclusive benefits as a premium member
Unlock exclusive benefits as a premium member
Unlock exclusive benefits as a premium member
Unlock exclusive benefits as a premium member
Unlock exclusive benefits as a premium member
Unlock exclusive benefits as a premium member
Unlock exclusive benefits as a premium member
Unlock exclusive benefits as a premium member
Current offers & deals for luxury hotels in Panama
Many of our partner hotels in Panama offer special conditions bookable through suitespot – from free nights to hotel credit.
| Hotel | Offer | Bookable until |
|---|---|---|
| Waldorf Astoria Panama | Up to 33% discount for stays of three nights or more | August 12, 2027 |
Your guide to the best luxury hotels in Panama
Hotel La Compañia Casco Antiguo · Panama CityFor a city break we recommend the Hotel La Compañia Casco Antiguo, set in a Jesuit monastery from 1688. Couples find peace at Nayara Bocas del Toro, an adults-only resort on a private island. Families and golfers stay at The Santa Maria Resort Panama City on the edge of the city. In the highlands, the Hotel La Compañía del Valle El Valle de Antón brings art and relaxation together with a sculpture park and spa.Wherever you stay: when you book through suitespot, you receive exclusive benefits at all our luxury hotels in Panama, depending on the hotel such as breakfast for two, a room upgrade subject to availability or a hotel credit.
At no extra cost: booking through suitespot costs the same as booking direct with the hotel – the benefits come on top, free of charge.
Where to stay in Panama: the capital, the Caribbean, the Pacific coast and the highlands – the right location for your 5-star hotel
Which of the best hotels in Panama suit you depends first of all on the region.
Sofitel Legend Casco Viejo · Panama CityThe capital: Nine of our twelve hotels are in Panama City. If you are after history, stay in the old town of Casco Viejo, a UNESCO World Heritage Site: at the Hotel La Compañia Casco Antiguo, built around the ruins of a Jesuit church, or at the Sofitel Legend Casco Viejo right on the water. If you want the skyline and the bay outside your window, book the JW Marriott Panama in Punta Pacífica. Our city guide shows which neighborhood suits your trip.
Nayara Bocas del Toro · PanamaThe Caribbean: In the Bocas del Toro archipelago, Nayara Bocas del Toro sits on the private island of Isla Frangipani, overlooking Dolphin Bay and Bastimentos Marine National Park. The resort is reserved for adults; you stay in overwater villas with their own pool or in bamboo treehouses high up in the mangroves.
The Pacific coast: About 90 minutes by car from the capital, near Río Hato, The Buenaventura Resort Panama lies right on the beach of the Riviera Pacífica. The low-rise resort is modeled on a Spanish colonial town with a plaza and has a golf course designed by Jack Nicklaus.
- Breakfast for two, every day
- Room upgrade subject to availability
- Hotel credit, e.g. US$100
- Early check-in and late check-out
- VIP service and personal advice
- Points and status in the hotel programme
At no extra cost: you pay the same rate as booking direct with the hotel – the suitespot benefits come on top, free of charge.
The highlands: In the crater of an extinct volcano, at around 600 meters above sea level and some 80 kilometers west of Panama City, the Hotel La Compañía del Valle El Valle de Antón has welcomed guests since 2025. A sculpture park with more than 200 works and the Elysium Spa make it a destination for art and relaxation.
New in Panama City
The Hyatt Regency Ciudad de Panamá opened in 2025 as the first Hyatt Regency in Central America, with furniture made by local artisans and bathrooms in green marble. The Marriott Hotel Panama has carried the Marriott name since 2023; from the hotel you walk straight into the Albrook Mall shopping center.
These luxury hotels in Panama have a pool – on the roof, by the sea and in a volcanic crater
Eleven of our twelve hotels have a pool. If you choose your 5-star hotel in Panama by its pool, you decide between rooftop, sea and nature.
JW Marriott Panama · Panama CityIn the capital: On the roof of the Hotel La Compañia Casco Antiguo you swim with a view over the old town and the Pacific, and in the evening the pool glows cobalt blue. The infinity pool at the Sofitel Legend Casco Viejo lies right on the water, and at the JW Marriott Panama two infinity pools on the 13th-floor deck seem to flow into the bay.
- Breakfast for two, every day
- Room upgrade subject to availability
- Hotel credit, e.g. US$100
- Early check-in and late check-out
- VIP service and personal advice
- Points and status in the hotel programme
Beyond the city: At Nayara Bocas del Toro the overwater villas have their own pool, and at the Hotel La Compañía del Valle El Valle de Antón the infinity pool sits in the middle of the volcanic crater. Families appreciate the outdoor pool with a children’s area and complimentary cabanas at The Santa Maria Resort Panama City.
Spa & wellness at the 5-star hotels in Panama: healing rituals, massages and calm in the crater
In the city: The Sofitel Spa with KOS Paris at the Sofitel Legend Casco Viejo offers treatments based on traditional healing rituals, along with a plunge pool, a tea room and a relaxation area. At The Santa Maria Resort Panama City the Espíritu Santo massage is named after Panama’s national flower, and at the Hotel La Compañia Casco Antiguo the spa is up on the roof.
The Santa Maria Resort Panama CityOn the island and in the highlands: At Nayara Bocas del Toro the Colibri Spa adds to the calm of the private island, and at the Hotel La Compañía del Valle El Valle de Antón the Elysium Spa is part of a stay in the crater.
Dining at Panama’s luxury hotels: a kitchen in a Jesuit chapel, fire above the rooftops and rum in a hideaway
In the old town, Restaurant 1739 at the Hotel La Compañia Casco Antiguo serves modern French cuisine in a former Jesuit chapel; a spiral staircase leads down to a 300-year-old wine cellar with tastings. At the Sofitel Legend Casco Viejo, Caleta under chef Lorenzo Di Gravio cooks creatively with fish and seafood from Panama, while up on the roof Ammi grills over an open fire.
W Panama · Panama CityOn the edge of the city, Mestizo at The Santa Maria Resort Panama City serves Panamanian small plates with Mediterranean influences, and the café pours Geisha coffee from Boquete.
Bars behind a hidden door and in a container
Behind a hidden door at the Sofitel Legend Casco Viejo lies the rum bar Arcano with rare rums, open Thursday to Sunday evenings. At the W Panama the Cargo bar sits in its own shipping container, a nod to the Panama Canal.
Award-winning and full of history: luxury hotels in Panama with Michelin Keys and a Forbes recommendation
Michelin Keys are awarded to hotels, not restaurants. One Key each goes to the Hotel La Compañia Casco Antiguo and the Sofitel Legend Casco Viejo, both in the old town of Casco Viejo.
Waldorf Astoria Panama · Panama CityRecommended in the Forbes Travel Guide are The Santa Maria Resort Panama City by the golf course and the Waldorf Astoria Panama on Calle Uruguay, which opened in 2013 as the first Waldorf Astoria in Latin America.
Hotels with history: The Hotel La Compañia Casco Antiguo brings together a Jesuit monastery from 1688, a university building from 1739 and a former department store from the early 20th century around a garden courtyard; it opened in 2022 after seven years of restoration. In 2023 the Sofitel Legend Casco Viejo moved into the 1917 clubhouse of the Club Unión, and it displays around a thousand works of art, most of them by Panamanian artists.
What a night at a 5-star hotel in Panama costs – destinations and prices at a glance
In Panama City a night starts at 148 € at the Marriott Hotel Panama by the Albrook Mall. In the old town you stay at the Hotel La Compañia Casco Antiguo from 268 €, with a two-night minimum stay, and at the Sofitel Legend Casco Viejo from 357 €.
Marriott Hotel Panama · Panama CityOutside the capital, the Hotel La Compañía del Valle El Valle de Antón in the highlands starts at 182 € and The Buenaventura Resort Panama on the Pacific coast at 200 €. The private island of Nayara Bocas del Toro in the Caribbean is well above that, from 1,168 €. You will find all other luxury hotels in Panama with their current prices in the hotel list below.
| Destination | Hotels | Price from | Our recommendation |
|---|---|---|---|
| Panama City | 9 | from 148 € | Hotel La Compañia Casco Antiguo |
| Caribbean, Pacific coast and highlands without their own destination page | 3 | from 182 € | Nayara Bocas del Toro |
How to combine: We recommend two to three nights in the capital, followed by a few days on the island, on the coast or in the highlands. Our travel advisors will plan your 5-star hotel in Panama for every stage of the trip with you.
Suites & family options in Panama
Suites in Panama range from treehouses to a party suite. At Nayara Bocas del Toro you stay in overwater villas with their own pool or in treehouses in the mangroves, at the Waldorf Astoria Panama in suites overlooking the bay, and the Extreme Wow Suite at the W Panama has its own DJ booth. Our travel advisors confirm layout and view before you book.
| Hotel | Destination | Suite categories (selection) | Largest suite |
|---|---|---|---|
| Waldorf Astoria Panama | Panama City | Condo Suite, Junior Suite, Studio Suite | – |
| JW Marriott Panama | Panama City | Curve Suite, Executive Suite, Grand Suite | – |
| Hotel La Compañia Casco Antiguo | Panama City | Francaise Suite, Junior Suite, La Grande Suite | – |
| Sofitel Legend Casco Viejo | Panama City | Imperial Suite, Junior Suite, Legendary Suite | – |
| Hotel La Compañía del Valle El Valle de Antón | El Valle de Antón | Junior Suite, Loft Suite, Master Suite | – |
| Marriott Hotel Panama | Panama City | Availability Suite, Suite | – |
| The Santa Maria Resort Panama City | Panama City | Executive Suite, Grand Suite, Master Suite | – |
| Hyatt Regency Ciudad de Panamá | Panama City | Deluxe Suite, Regency Deluxe Suite, Regency Suite | – |
Earn points & use your status in Panama
In Panama, Marriott Bonvoy ranges from the JW Marriott Panama on the bay to The Buenaventura Resort Panama on the Pacific coast, and World of Hyatt applies at both La Compañía hotels and at the Hyatt Regency Ciudad de Panamá. Add ALL (Accor) at the Sofitel Legend Casco Viejo, Hilton Honors at the Waldorf Astoria Panama, IHG One Rewards at the InterContinental Miramar Panama and Leaders Club at Nayara Bocas del Toro. Because suitespot books at direct rates, points, elite nights and status benefits count just as they do on a direct booking.
| Program | Hotels | Examples in Panama |
|---|---|---|
| Marriott Bonvoy | 5 hotels | JW Marriott Panama, Marriott Hotel Panama, The Santa Maria Resort Panama City … |
| World of Hyatt | 3 hotels | Hotel La Compañia Casco Antiguo, Hotel La Compañía del Valle El Valle de Antón, Hyatt Regency Ciudad de Panamá |
| ALL (Accor) | 1 hotel | Sofitel Legend Casco Viejo |
| Hilton Honors | 1 hotel | Waldorf Astoria Panama |
| IHG One Rewards | 1 hotel | InterContinental Miramar Panama |
| Leaders Club | 1 hotel | Nayara Bocas del Toro |
More luxury destinations nearby
These countries combine well with a trip in Panama — or make a fitting alternative for your next booking:
Frequently asked questions about luxury hotels in Panama
What does a night at a luxury hotel in Panama cost?
In Panama City from 148 € at the Marriott Hotel Panama. In the old town, the Hotel La Compañia Casco Antiguo starts at 268 € (minimum two nights). Outside the capital you start from 182 € in the highlands at the Hotel La Compañía del Valle El Valle de Antón, while the private island of Nayara Bocas del Toro begins at 1,168 €.
Can I earn points at the luxury hotels in Panama?
Yes: Marriott Bonvoy applies at the JW Marriott Panama, for example, World of Hyatt at the Hotel La Compañia Casco Antiguo, ALL (Accor) at the Sofitel Legend Casco Viejo and Hilton Honors at the Waldorf Astoria Panama. Points and elite nights count just as they do on a direct booking.
Which luxury hotel in Panama is on the beach?
The Buenaventura Resort Panama lies right on the Pacific beach of the Riviera Pacífica. In the Caribbean you stay at Nayara Bocas del Toro on a private island with overwater villas, and in Panama City at the Sofitel Legend Casco Viejo right on the water of the old town.
Which hotel in Panama is right for families?
In Panama City, The Santa Maria Resort Panama City with a children’s area by the pool, complimentary cabanas and babysitting. The JW Marriott Panama has a smaller, warmer pool for children next to its infinity pools.
Is a 5-star hotel in Panama worth it outside the capital?
Yes, above all for nature and peace: in the Caribbean you stay at Nayara Bocas del Toro, on the Pacific coast at The Buenaventura Resort Panama with its beach and golf course, and in the volcanic crater of El Valle de Antón at the Hotel La Compañía del Valle El Valle de Antón.
Which hotels in Panama hold Michelin Keys?
The Hotel La Compañia Casco Antiguo and the Sofitel Legend Casco Viejo hold one Key each, both in the old town of Panama City.
Which luxury hotels in Panama are new?
In 2025 the Hotel La Compañía del Valle El Valle de Antón opened in the highlands and the Hyatt Regency Ciudad de Panamá in Panama City. Since 2023 the Sofitel Legend Casco Viejo has welcomed guests in the former Club Unión.
Which hotels in Panama have a golf course?
The Santa Maria Resort Panama City on the edge of Panama City and The Buenaventura Resort Panama on the Pacific coast, both with a course by Jack Nicklaus.
Which is the most expensive luxury hotel in Panama?
Nayara Bocas del Toro on its private island in the Caribbean, from 1,168 € a night.
Which are the best hotels in Panama?
That depends on your trip: for history the Hotel La Compañia Casco Antiguo in the old town, for the sea on your doorstep the Sofitel Legend Casco Viejo, for families and golf The Santa Maria Resort Panama City and for a private island Nayara Bocas del Toro.
